Chromosome cohesion: A polymerase for chromosome bridges
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چکیده
منابع مشابه
Chromosome cohesion: A polymerase for chromosome bridges
How do cells ensure that sister chromatids produced during DNA replication stay connected with each other until their separation in anaphase? New insight is provided by the discovery of DNA polymerase kappa, which has been found to be required for building the connections between sister chromatids.
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Ever since the founding work of Walther Fleming more than a century ago, the process by which one cell divides to create two daughters has fascinated biologists. But only now are we beginning to understand the mechanisms that underlie the coordinated distribution of the duplicated chromosomes — sister chromatids — to the two daughters when a eukaryotic cell divides. At the heart of this process...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2000
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(00)00709-0